Ghana coach Chris Hughton has made three changes to the team that started in their opening World Cup qualifier against Madagascar last Friday.
Daniel Amartey, Alidu Seidu and Mohammed Kudus have been replaced by Kassim Nuhu Adams, Denis Odoi and Andre Ayew, respectively, in the starting XI for the game against Comoros.
Kundous was benched after missing the team’s last practice session with a back injury. Hughton, however, decided to stick with Richard Ofori in the post.
Gideon Mensah and Nicholas Opoku completed the back four, with Abdul Salis Samed and Baba Iddrisu once again trusted in the middle of the park.
Jordan Ayew also kept his place on the left, with match-winner against Madagascar Inaki Williams operating from the right.
Captain Andre Ayew returned to the starting line-up for the first time in months and occupied the No.10 role in the absence of the injured Kudus.
Antoine Semeneu led the line as the team’s main striker as the Black Stars aimed to make it two wins from two World Cup qualifiers.
Comoros made the brightest start to the game enjoying the lion’s share of possession, but it was Ghana who carved out the first real opening after six minutes.
Williams played Semenyo through on goal, but the Bournemouth striker failed to make the one-on-one opportunities count, sending his shot into the side netting.
Four minutes later, Comoros made their first dangerous foray into Ghana’s half, Yusuf attempting a long-range strike that flew wide of the target.
Ofori was called upon a few times in the first half, keeping out Selemani’s shot before turning away Burhane’s effort for a corner.
Ghana would miss another chance to score the opener when Williams found Jordan Ayew with an accurate cross, but the Crystal Palace striker could not get his header on target.
The Black Stars were finally punished for their poor defending three minutes before half-time when Maolinda burst through the Ghanaian back line to score – against the run of play.
Hughton brought on Kudus for Andre Ayew at the start of the second half and Ernest Nuamah and Majeed Ashimeru would later join the fray, but Ghana continued to struggle to create clear-cut chances.
Nwama, however, was unlucky not to get an equalizer when his goal was disallowed by the referee, despite appearing to have clearly won an aerial challenge on the Comoros keeper.
Despite pushing on more men in the final 15 minutes, Comoros held on for a famous win – their second successive victory over the Black Stars after beating Ghana in the last AFCON.
Meanwhile, the Coelacanths have now moved to the top of Group I of the African World Cup qualifiers with six points, with Ghana dropping to fourth after Tuesday’s disappointing defeat.